Platonism in this regard is philosophically significant, in that it challenges the physicalist idea that reality is exhausted by the physical, because it entails a sector of reality that is non-physical and contains objects which are removed from the causal, spatio-temporal hierarchy observed in physical science.
It also presents issues to naturalistic theories of knowledge, for mathematics is knowledge we posses, which is abstract, and this would be hard for naturalistic theories to account for.